Brin-bd11
WebOct 1, 2010 · The BRIN-BD11 is a novel insulin-secreting cell that responds to various ranges of pharmacological modulators of insulin secretion … WebDec 11, 2024 · The BRIN-BD11 cell line offers an easy-to-utilize, cell-based system that has been reported to provide a stable, reproducible, and robust system for the study of pancreatic β-cell function. Recent research has explored parameters of mitochondrial metabolism and metabolic adaptations of this cell line in response to various stimuli.
Brin-bd11
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WebDefine brin. brin synonyms, brin pronunciation, brin translation, English dictionary definition of brin. n 1. one of two filaments of silk combined by the silkworm to form a … WebApr 11, 2024 · (A) BRIN‐BD11 cells were cultured (24 h) with test peptides (10 −8 and 10 −6 M) and proliferation detected using Ki-76 staining. (B) BRIN‐BD11 were cultured (24 h) with test peptides (10 −8 and 10 −6 M) in the presence of a cytokine cocktail and apoptosis detected using the TUNEL assay. All values are mean ± SEM (n=3).
WebBRIN-BD11 is a hybrid cell line formed by the electrofusion of a primary culture of NEDH rat pancreatic islets with RINm5F (a cell line derived from a NEDH rat insuliinoma). BRIN … WebNov 3, 2016 · The cell proliferation rate of BRIN-BD11 cells treated with H 2 O 2 (125 or 250 μM) dropped over 50 % at 6 h post-treatment (Fig. 3a). At 24 h post-treatment, the cell proliferation ratio of BRIN-BD11 cells that were treated with the lower concentration of H 2 O 2 (125 μM) returned to original levels.
WebJan 1, 2006 · The stimulus-secretion coupling for hypotonicity-in-duced insulin release was investigated in BRIN–BD11 cells. A 50 mM decrease in extracellular NaCl caused a twofold increase in insulin release. Webwe will update the requested part number on or product list of datasheet as we do it on a daily basis. thank you again and we will keep your posted. Search Partnumber : …
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WebJul 7, 2009 · BRIN-BD11 cells also showed pronounced insulin responses to leucine, KIC, L-arginine, L-alanine and palmitic acid. All the cell lines tested gave significant responses to the neurotransmitters carbachol and glibenclamide with increased insulin release. A comparison was made between the functional characteristics of the various cell lines with ... dori vana plumbingWebDec 1, 2006 · l-Alanine is consumed at high rates in both BRIN-BD11 cells and rat islets (∼2 and 8 μmol/mg protein/20 min for BD11 cells and islets, respectively ). Addition of 10 mmol/l l-alanine to 16.7 mmol/l glucose significantly increased glucose consumption in BRIN-BD11 cells , suggesting a critical role for l-alanine in β-cell function. dorival x jesusWebDec 11, 2024 · The BRIN-BD11 cell line offers an easy-to-utilize, cell-based system that has been reported to provide a stable, reproducible, and robust system for the study of … raca to vndWebMar 15, 2024 · This study was undertaken to investigate the effects of an ethanolic (80% v/v) extract of A. squamosa (EEAS) leaves in vitro on insulin secretion from clonal pancreatic BRIN BD11 β-cells and mouse islets, including mechanistic studies on the effect of EEAS on membrane potential and intracellular calcium ion concentration. Additional in … dorivor o\\u0027simliklarWebJun 27, 2015 · Aims G-protein-coupled receptor 39 (GPR39) has been implicated in glucose homoeostasis, appetite control and gastrointestinal tract function. Methods This study used clonal BRIN-BD11 cells and mouse pancreatic islets to assess the insulin-releasing actions of trace metals believed to act via GPR39, and the second messenger pathways … dorivar ruiz diaz ksuWebMoreover, the mode of action of UJ was analyzed in palmitate (PA)-induced steatotic human HuS-E/2 hepatocytes and in hyperglycemia-simulating rat BRIN-BD11 pancreatic β cells. In PA-induced steatotic human hepatocytes, UJ treatment promoted lipid clearance via pAMPK, pACC and CPT-1 upregulation and SREBP-1c downregulation. dori zambonidorivor uz